#13 of the Punisher has Frank steal an unidentified piece of technology from an illegal auction which use to belong to Doc Ock and recent interviews have suggested that Frank will acquire something which will level the playing field a little between him and the super-powered community.
All of that said, Marvel are hardly going to let a creator allow Frank to kill off high profile Avengers, so whilst I'm optimistic about the new series and it seems to be getting the kind of publicity that the Punisher has lacked for years it seems the case that the character will face the same restrictions as before - namely that he will never be allowed to kill off anyone of note.
Oh, I know he's not going to kill anyone but the fact that he can even take the whole team on his own is rather abused, even with advance weaponry. Cable may have been able to take down 3 Avengers but the had future tech, the element of surprise, and his super powers.
Plus, what contrive reason would he have to attack the Avengers?