Can't wait to see who the next big bad cosmic menace will be!
In terms of a Big Bad leading them, geez, in space, no one can hear you scream...what movie is that from? Oh, Alien.
I meant to say, in MU outer space and outer dimensions, it could be Infinity, or the In-Betweener, or Kang, Immortus, Nebula, or someone far more earth-bound traditionally, like we've just seen Ultron, the Super Adaptoid, and the High Evolutionary used.
It could be the Man-Beast, Maelstrom, Centurious, or even a demon like Mephisto or Dormammu.