I found one of the main theme's of that continuity to be the 2 togather after the loss of May after revolations. Aspecially after Norman's return, that has always haunted Peter and is what made him such a top stand out villian because of how personal his battle with Spider-Man was, beyond Gwen's death long ago. But after BND, one of Joe Q's cherry on top was not only undoing their marriage and strong relationship togather but never having mj pregnant since that aged Peter further.
All I can say about that era in Spider-Man Comics when Norman Osborn assumed the Lex Luthor Role is, that it is the SHIZ AND IIITTTT''SSSS AAAAAAAAWWWWWEEEEEEESSSSSSOOOOOOOOOMMMMMMMMMMMEEEEEEEEEE !!!!!!!!!!!!!