1. Did he get dumped off a bridge by Norman?
2. Did the Jackal have a crush on him and clone him a bunch of times?
3. Did one of Gwen's female villains reveal she had Peter's children and then super age them?
Never read the issue but according to a quick web search, Peter was helping out with Curt Conners research or was doing it independently and became the Lizard. He was killed by Gwen and when reverting back to being Peter the cops just happened to show up making Spider-Woman\Gwen an outlaw.
The Disgruntled Greek