It is possible that Mysterio knows and does not care. Not every villain wants to learn the hero identity and attack them through loved ones.

Joker I am certain knows Bruce is batman, but to Joker, Batman is the enemy not Bruce.


Also I cannot see how Mysterio could have changed time to prevent the marriage, healed Aunt May and did a world wide mind wipe. I don't think his powers are quite that strong.

Also I really do not approve of trying to retcon Mephisto out of OMD. Who else would want to disrupt and remove Peter and MJ's marriage except maybe Kang or Immortus as they see in the future that descendants of Spider-man would be a problem for their future schemes?

Marvel needs to take their lumps for using Mephisto to get Peter out of the bad corner he was written into and END THE MEPHISTO MINDWIPE.