Yes, Dean and Terri had great chemistry. Fortunately most Superman/Lois actor pairings did.
Christopher and Margot are the best pair but being challenged by Tyler and Elizabeth, Then Dean and Teri and Gerard and Staci (though Stacy played Lana).
The two pairings that did not have good chemistry were Brandon and Kate and Henry and Amy.
Chemistry is an odd thing. You can have actors who off-screen have strong chemistry but on-screen it does not carry over. The sweet spot is when actor pairings can bring their natural chemistry onto their screen performance. Tyler and Elizabeth do this big time. It's so fun the watch their interviews together and how natural and playful they are with each other and to see them reproduce their great vibe on screen as Clark and Lois.
What current couple has for them in additional to real chemistry is real family dynamic, as this version of Superman is facing more realistic challenges of being a Husband and father now!